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Botulinum Toxin How Deadly? (Deep Research)

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The median lethal dose for humans has been estimated at 2 nanograms of botulinum toxin per kilogram of bodyweight, which is approximately 3 times greater than in foodborne cases. Following inhalation of the toxin, symptoms become visible between 1–3 days, with longer onset times for lower levels of intoxication.

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Related Questions

1How Does Botulinum Toxin Cause Death??

Botulism (“BOT-choo-liz-um”) is a rare but serious illness caused by a toxin that attacks the body’s nerves and causes difficulty breathing, muscle paralysis, and even death.

2Is Botulism Toxin Deadly?

Botulinum toxins, if prepared as an aerosol, have the potential to be potent biological weapons. One gram of an aerosolized botulism toxin is enough to kill about a million people, and a human toxic dose is on the order of a billionth of a gram.

3Can You Survive Botulinum Toxin?

Survival and Complications

Others die from infections or other problems caused by being paralyzed for weeks or months. Patients who survive botulism may have fatigue and shortness of breath for years afterward and may need long-term therapy to help them recover.

4Is Botulinum Toxin The Deadliest Poison?

Botulinum toxin

Scientists differ about the relative toxicities of substances, but they seem to agree that botulinum toxin, produced by anaerobic bacteria, is the most toxic substance known. Its LD50 is tiny – at most 1 nanogram per kilogram can kill a human.

5Does Botulism Cause Death?

Symptoms of botulism usually start with weakness of the muscles that control the eyes, face, mouth, and throat. This weakness may spread to the neck, arms, torso, and legs. Botulism also can weaken the muscles involved in breathing, which can lead to difficulty breathing and even death.

6How Long Until Botulism Is Fatal?

Respiratory failure generally causes death in untreated individuals. Symptoms generally begin 12 to 36 hours after consuming the toxin in food but in rare cases symptoms can occur as early as 6 hours or as late as 2 weeks after exposure. Most people recover from botulism but the recovery period can take months.

7How Serious Is Botulism?

Botulism is a very rare but life-threatening condition caused by toxins produced by Clostridium botulinum bacteria. These toxins are some of the most powerful known to science. They attack the nervous system (nerves, brain and spinal cord) and cause paralysis (muscle weakness).